Search Papua New Guinea: Bisoprolol and hydrochlorothiazide

bis-oh-PROE-lol FUE-ma-rate, hye-droe-klor-oh-THYE-a-zide

Commonly used brand name(s)

In the U.S.

Ziac

Available Dosage Forms:

Tablet

Therapeutic Class: Beta-Adrenergic Blocker, Cardioselective/Thiazide Combination

Pharmacologic Class: Bisoprolol

Chemical Class: Thiazide

Uses For bisoprolol and hydrochlorothiazide

Bisoprolol and hydrochlorothiazide combination is used to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Bisoprolol is a beta-blocker. It works by affecting the response to some nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart.

Hydrochlorothiazide is a thiazide diuretic (water pill). It reduces the amount of water in the body by increasing the flow of urine, which helps lower the blood pressure.

bisoprolol and hydrochlorothiazide is available only with your doctor's prescription.

Before Using bisoprolol and hydrochlorothiazide

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For bisoprolol and hydrochlorothiazide, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to bisoprolol and hydrochlorothiazide or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of bisoprolol and hydrochlorothiazide combination in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of bisoprolol and hydrochlorothiazide combination in the elderly. However, elderly patients are more likely to have age-related liver or kidney problems, which may require an adjustment in the dose for patients receiving bisoprolol and hydrochlorothiazide combination.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking bisoprolol and hydrochlorothiazide, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using bisoprolol and hydrochlorothiazide with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Dofetilide

Using bisoprolol and hydrochlorothiazide with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acetyldigoxin

Albuterol

Amiodarone

Arformoterol

Arsenic Trioxide

Bambuterol

Bitolterol

Broxaterol

Clenbuterol

Clonidine

Colterol

Deslanoside

Digitalis

Digitoxin

Digoxin

Diltiazem

Dronedarone

Droperidol

Fenoldopam

Fenoterol

Flecainide

Formoterol

Hexoprenaline

Indacaterol

Isoetharine

Ketanserin

Levalbuterol

Levomethadyl

Lithium

Metaproterenol

Metildigoxin

Ouabain

Pirbuterol

Procaterol

Proscillaridin

Reproterol

Rimiterol

Ritodrine

Salmeterol

Sotalol

Terbutaline

Tretoquinol

Tulobuterol

Verapamil

Using bisoprolol and hydrochlorothiazide with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acarbose

Aceclofenac

Acemetacin

Acetohexamide

Alacepril

Alclofenac

Alfuzosin

Amlodipine

Apazone

Arbutamine

Aspirin

Benazepril

Benfluorex

Benoxaprofen

Bepridil

Bromfenac

Bufexamac

Bunazosin

Captopril

Carbamazepine

Carprofen

Celecoxib

Chlorpropamide

Cholestyramine

Cilazapril

Clometacin

Clonixin

Cyclophosphamide

Delapril

Dexketoprofen

Diclofenac

Diflunisal

Digoxin

Dipyrone

Doxazosin

Droxicam

Enalaprilat

Enalapril Maleate

Etodolac

Etofenamate

Felbinac

Felodipine

Fenbufen

Fenoprofen

Fentiazac

Floctafenine

Flufenamic Acid

Flurbiprofen

Fosinopril

Ginkgo

Gliclazide

Glimepiride

Glipizide

Gliquidone

Glyburide

Gossypol

Guar Gum

Ibuprofen

Ibuprofen Lysine

Imidapril

Indomethacin

Indoprofen

Insulin

Insulin Aspart, Recombinant

Insulin Glulisine

Insulin Lispro, Recombinant

Isoxicam

Ketoprofen

Ketorolac

Lacidipine

Lercanidipine

Licorice

Lisinopril

Lornoxicam

Magnesium Salicylate

Manidipine

Meclofenamate

Mefenamic Acid

Meloxicam

Metformin

Methyldopa

Mibefradil

Miglitol

Moexipril

Moxisylyte

Nabumetone

Naproxen

Nepafenac

Nicardipine

Nifedipine

Niflumic Acid

Nilvadipine

Nimesulide

Nimodipine

Nisoldipine

Nitrendipine

Oxaprozin

Oxyphenbutazone

Pentopril

Perindopril

Phenoxybenzamine

Phentolamine

Phenylbutazone

Pirazolac

Piroxicam

Pirprofen

Pranidipine

Prazosin

Propyphenazone

Proquazone

Quinapril

Ramipril

Repaglinide

Rifapentine

Salicylic Acid

Salsalate

Spirapril

St John's Wort

Sulindac

Suprofen

Tamsulosin

Temocapril

Tenidap

Tenoxicam

Terazosin

Tiaprofenic Acid

Tolazamide

Tolbutamide

Tolmetin

Topiramate

Trandolapril

Trimazosin

Troglitazone

Urapidil

Zofenopril

Zomepirac

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of bisoprolol and hydrochlorothiazide

In addition to the use of bisoprolol and hydrochlorothiazide, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that bisoprolol and hydrochlorothiazide will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Dosing

The dose of bisoprolol and hydrochlorothiazide will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of bisoprolol and hydrochlorothiazide. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets):
- For high blood pressure:
  - Adults—One or two tablets per day, given as a single dose or in divided doses. Your doctor may adjust your dose if needed.
  - Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of bisoprolol and hydrochlorothiazide, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using bisoprolol and hydrochlorothiazide

It is very important that your doctor check your progress at regular visits to make sure bisoprolol and hydrochlorothiazide is working properly. Blood and urine tests may be needed to check for unwanted effects.

bisoprolol and hydrochlorothiazide may cause or worsen heart failure in some patients. Check with your doctor right away if you are having chest pain or discomfort; dilated neck veins; extreme fatigue; irregular breathing; an irregular heartbeat; shortness of breath; swelling of the face, fingers, feet, or lower legs; weight gain; or wheezing.

bisoprolol and hydrochlorothiazide may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash; itching; hoarseness; trouble breathing; trouble swallowing; or any swelling of your hands, face, lips, tongue, or throat while you are using bisoprolol and hydrochlorothiazide.

Do not interrupt or stop taking bisoprolol and hydrochlorothiazide without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are taking before stopping it completely. Some conditions may become worse when the medicine is stopped suddenly, which can be dangerous.

bisoprolol and hydrochlorothiazide may cause changes in your blood sugar levels. Also, bisoprolol and hydrochlorothiazide may cover up signs of low blood sugar, such as a rapid pulse rate. Check with your doctor if you have these problems or if you notice a change in the results of your blood or urine sugar tests.

Make sure any doctor or dentist who treats you knows that you are using bisoprolol and hydrochlorothiazide. Your doctor will tell you if you are going to stop taking bisoprolol and hydrochlorothiazide several days before having surgery or medical tests.

Stop using bisoprolol and hydrochlorothiazide and check with your doctor immediately if blurred vision, difficulty in reading, eye pain, or any other change in vision occurs during or after treatment. This could be a sign of a serious eye problem. Your doctor will want you to have your eyes checked by an ophthalmologist (eye doctor).

Check with your doctor right away if you start having dry mouth, increased thirst, muscle cramps, nausea or vomiting, unusual tiredness or weakness, severe drowsiness or dizziness, seizures, a decrease in urine, or a fast heartbeat while you are using bisoprolol and hydrochlorothiazide. These may be symptoms of dehydration or mineral imbalance.

bisoprolol and hydrochlorothiazide may cause some people to become less alert than they are normally. If this side effect occurs, do not drive, use machines, or do anything else that could be dangerous if you are not alert while taking bisoprolol and hydrochlorothiazide.

bisoprolol and hydrochlorothiazide may cause your skin to be more sensitive to sunlight than normal. Be sure to apply sunscreen before going outside, and wear protective clothing and a hat.

Do not take other medicines unless they have been discussed with your doctor. This especially includes prescription or nonprescription (over-the-counter) medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems, since they may increase your blood pressure.

bisoprolol and hydrochlorothiazide Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

Bloating or swelling of the face, arms, hands, lower legs, or feet

chest pain or discomfort

lightheadedness, dizziness, or fainting

rapid weight gain

shortness of breath

slow or irregular heartbeat

tingling of the hands or feet

unusual tiredness or weakness

unusual weight gain or loss

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Anxiety

blurred vision

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

change in consciousness

chills

cold, clammy skin

cold sweats

confusion as to time, place, or person

cool, pale skin

cough

decrease in amount of urine

depression

difficulty breathing

dilated neck veins

dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position

drowsiness

dry mouth

extreme fatigue

fast or pounding heartbeat or pulse

fast, weak pulse

frequent urination

hallucinations

holding false beliefs that cannot be changed by fact

increased hunger

increased thirst

increased volume of pale, dilute urine

irregular breathing

irritability

loss of appetite

loss of consciousness

mood changes

muscle pain or cramps

nausea or vomiting

nervousness

nightmares

no breathing

noisy breathing

not able to pass urine

numbness or tingling in the hands, feet, or lips

pain or aching in the lower legs

seizures

shakiness

slurred speech

sweating

swelling of the face, hands, fingers, feet, ankles, or lower legs

tightness in the chest

trembling

troubled breathing

unconsciousness

unusual drowsiness, dullness, or feeling of sluggishness

unusual excitement, nervousness, or restlessness

very drowsy or sleepy

weakness and heaviness of legs

weight gain

wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Acid or sour stomach

belching

decreased interest in sexual intercourse

diarrhea

difficulty with moving

heartburn

inability to have or keep an erection

indigestion

joint pain

loss in sexual ability, desire, drive, or performance

muscle aching or stiffness

sleepiness

stomach discomfort, upset, or pain

swollen joints

Rare

Runny nose

sneezing

stuffy nose

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: bisoprolol and hydrochlorothiazide side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More bisoprolol and hydrochlorothiazide resources

Bisoprolol and hydrochlorothiazide Side Effects (in more detail)
Bisoprolol and hydrochlorothiazide Dosage
Bisoprolol and hydrochlorothiazide Use in Pregnancy & Breastfeeding
Drug Images
Bisoprolol and hydrochlorothiazide Drug Interactions
Bisoprolol and hydrochlorothiazide Support Group
11 Reviews for Bisoprolol and hydrochlorothiazide - Add your own review/rating

Compare bisoprolol and hydrochlorothiazide with other medications

High Blood Pressure

Search Papua New Guinea

Tuesday, October 25, 2016

Bisoprolol and hydrochlorothiazide